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Japanese Pharmacology & Therapeutics(JPT)

Vol.27 Suppl.5 1999

*With abstract in English  **In English

■Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199)

Pharmacokinetic studies of (±)-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyrid-2-yl)methyl]sulfinyl}- 1H -imidazo[4,5-b]pyridine(TU-199)(VIII)
-Metabolism of TU-199 in human-

M.Kinbara, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1163-75


Phase I study of TU-199
-Safety,pharmacology and pharmacokinetics with single and multiple dosing-

K.Saigenji, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1177-200


Gastric acid serection-inhibitory effect of TU-199 by 24-hour intragastric pH monitoring
-A trial of clinical pharmacology with healthy volunteers-

M.Inoue, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1201-9


A pharmacokinetic study of TU-199(benatoprazole) in aged healthy volunteers

M.Kinbara, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1211-8


Clinical evaluation of TU-199(benatoprazole) in patients with gastric or duodenal ulcer
-Early phase II study-

T.Nakamura, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1219-35


Dose finding study of the new anti-ulcer agent TU-199(benatoprazole) on gastric and duodenal ulcers
-Clinical late phase II study-

T.Nakamura, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1237-64


Clinical evaluation of bed-time treatment with a new proton pump inhibitor TU-199(benatoprazole)in peptic ulcers

T.Toyota, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1265-75


Clinical study of TU-199(benatoprazole), a new proton pump inhibitor
-Effect on endocrine function and healing in patients with gastric and duodenal ulcer-

A.Hayakawa, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1277-98


Effects of the new anti-ulcer agent TU-199(benatoprazole) on stomal ulcers

H.Niwa, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1299-302


Clinical usefulness of TU-199(benatoprazole), a new proton pump inhibitor on reflux esophagitis

S.Kishi, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1303-15


Clinical evaluation of TU-199(benatoprazole)in reflux esophagitis

T.Nakamura, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1317-27


Zollinger-Ellison syndrome successfully treated with a new proton pump inhibitor TU-199
-Report of a case-

M.Ichikawa, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1329-31


Treatment of TU-199 on Zollinger-Ellison syndrome
-A case report-

R.Hosotani, et al.

Jpn Pharmacol Ther 1999 27(Suppl.5) s1333-9