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Japanese Pharmacology & Therapeutics(JPT)

Vol. 26 Suppl. 2 1998

*With abstract in English

■The Record of the Fifth Meeting of the Japanese Study Group for the Pathophysiology of the Liver '97

Opening Remarks

T. Namihisa

Jpn Pharmacol Ther 1998 26(Suppl. 2) s257


1.Contribution of Na+-taurocholic acid cotransporting polypeptide (Ntcp) and organic anion transporting polypeptide (oatp) to the hepatic uptake of ligands into rat hepatocyte

H. Suzuki, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s265-73


2.Comparison of the biliary excretion using bile canalicular membrane vesicles (CMV) prepared from human and rat liver

K. Niinuma, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s275-81


3.Functional analysis of transfected rat cMOAT product in MDCK cells

S. Kinoshita, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s283-8


4.Induction of the expression of transporters in the rat liver

K. Ogawa, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s289-94


5.Functional analysis of rat cMOAT in cDNA transfected mammalian cells

K. Ito, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s295-9


6.Biliary excretion of heavy metals in Eisai hyperbilirubinemic rat

N. Sugawara, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s301-4


7.Transcytotic vesicle fusion with cholestatic rat canalicular membranes

H. Hyogo, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s305-7


8.An ultrastructural change in the pericanalicular region of rat liver under the organic anion-induced cholestasis

S. Tazuma, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s309-10


【Discussion 1-8】

Jpn Pharmacol Ther 1998 26(Suppl. 2) s311-6


9.Study of 3β,7β-dihydroxy-5β-cholan-24-oic acid (iso UDCA) metabolism in human

K. Nakamura, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s317-21


10.Effect of bile acid glucuronide and sulfate on biliary phenolphthalein glucuronide excretion

K. Kitaura, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s323-5


11.UDCA effect on signal transduction in the cholestatic hamster model

Y. Matsuzaki, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s327-32


12.Effects of cholecystectomy and administration of anion exchange rersin on bile acid and cholesterol metabolism

G. Yamashita, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s333-5


13. Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis

H. Koga, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s337-40


14.Ursodeoxycholic acid reduces expression of heat shock protein in the liver of primary biliary cirrhosis

S. Sakisaka, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s341-3


【Discussion 9-14】

Jpn Pharmacol Ther 1998 26(Suppl. 2) s345-8


15.Relationship between regional hepatic perfusion index and regional hepatic blood volume using positron emission tomography

H. Taniguchi, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s349-53*


16.The influence of restraint condition on hemodynamics in normal and portal vein stenosed concious rats

H. Terada, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s355-60*


17.A study of a change of serum total bile acid before and after endoscopic injection sclerotherapy for esophageal varices

K. Hashizume, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s361-4


18.Metabolic and hormonal alterations observed after TIPS and B-RTO procedures in cirrhotic patients

K. Hamano, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s365-70


19.Plasma adrenomedullin concentrations in patients with liver cirrhosis and its relation to ascites and renal function

H. Kojima, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s371-6


【Discussion 15-19】

Jpn Pharmacol Ther 1998 26(Suppl. 2) s377-9


20.Formation of gap junction and its biological significance in rat liver with hepatocellular carcinoma

A. Muramatsu, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s381-4


21.Demonstration of the histological change and cell differentiation in the mouse liver during ontogenesis, using the roller tube technique

S. Tanaka, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s385-8


22.Development of gap junctional intercellular communication in the liver during ontogenesis

M. Iwai et al

Jpn Pharmacol Ther 1998 26(Suppl. 2) s389-92


23.The expression of epimorphin in human liver

M. Hirose, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s393-5


24.Lobular heterogeneity of impaired hepatocyte tight junction in common bile duct-ligated rat

T. Kawaguchi, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s397-99


【Discussion 20-24】

Jpn Pharmacol Ther 1998 26(Suppl. 2) s401-3


25.Enhanced hepatic lipid peroxidation in chronic hepatitis C

F. Kageyama, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s405-8


26.Effects of Chinese animal crude drugs such as goou (bovine gallstone) and yutan (bear gall powder) on the hepatic lipid peroxidation

T. Nakashima, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s409-12


27.Transient urinary alkarization on chronic liver disease.

S.Sezai et al

Jpn Pharmacol Ther 1998 26(Suppl. 2) s413-6


28.Variation of blood endotoxin level in the course of acute obstructive suppurative cholangitis (AOSO, using endotoxin-specific quantitative limulus assay

Y. Yajima

Jpn Pharmacol Ther 1998 26(Suppl. 2) s417-22


29.The instrumental quantification of yellow skin

T. Suzuki, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s423-5


30.Endogenous hyaluronan loading test in patients with chronic liver diseases

Y. Idobe, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s427-31


31.Significance of the ratio of branched chain amino acid to tyrosine (BTR) in diagnosis and follow up of patients with chronic liver diseases
-The ratio of branched chain amino acid to tyrosine (BTR) in chronic liver diseases-

N. Kawamura, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s433-7


32.Measurement of serum trombopoietin (TPO) level in patients with liver disease

N. Kato, et al.

Jpn Pharmacol Ther 1998 26(Suppl. 2) s439-43*


【Discussion 25-32】

Jpn Pharmacol Ther 1998 26(Suppl. 2) s445-7


Closing Remarks

K. Kamisaka

Jpn Pharmacol Ther 1998 26(Suppl. 2) s449