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Japanese Pharmacology & Therapeutics(JPT)

Vol. 48 No. 2 2020

■ ORIGINAL ARTICLES

Nonclinical investigation of dotinurad on the risk of liver toxicity

M. Yamada, et al.

Jpn Pharmacol Ther 2020 48(2)157-64


Effects of formulation-modified esflurbiprofen patch (LOQOA® tape) on the transepidermal water loss and the exfoliation of stratum corneum of the skin in rabbits

K. Arima, et al.

Jpn Pharmacol Ther 2020 48(2)167-74


The effects of bofutsushosan and daisaikoto on plasma lipids and hepatic fatty drops in mice fed a high-fat diet

S. Sakamoto, et al.

Jpn Pharmacol Ther 2020 48(2)175-81


Evaluating safety and efficacy in retrospective analysis after switching drug to topiroxostat among patients with hyperuricemia study
– SANADA study –

S. Tohyo

Jpn Pharmacol Ther 2020 48(2)183-9


Chondroitin sulfate improves knee-extensor strength
– A randomized, double-blind, placebo-controlled study –

K. Yamada, et al.

Jpn Pharmacol Ther 2020 48(2)191-5


The effect of the oral probiotic on the periodontal status in healthy adults, randomized, double-blind, placebo-controlled parallel-group comparative study

T. Matsuoka, et al.

Jpn Pharmacol Ther 2020 48(2)197-202


Safety evaluation of excessive rose hip extract intake in healthy subjects
– A randomized, placebo-controlled, double-blind, parallel-group study –

A. Nagatomo, et al.

Jpn Pharmacol Ther 2020 48(2)203-14


Fasting blood glucose-lowering effects of salted rice koji (Shiokoji) in mildly hyperglycemic adults
– A randomized, double-blind, placebo-controlled parallel-group study –

A. Nakamura, et al.

Jpn Pharmacol Ther 2020 48(2)215-24


Effects of feeding hesperidin derived from fermented tea leaves made by tea-rolling processing of thinned satsuma mandarin fruit and green tea leaves on blood pressure
– Randomized, double-blind, placebo-controlled, parallel-group comparative study –

K. Tanaka, et al.

Jpn Pharmacol Ther 2020 48(2)225-35


Effects of oral use of phytosphingosine on skin moisturizing in healthy adults
– A 12-week double-blind, randomized, placebo-controlled trial –

A. Nishide, et al.

Jpn Pharmacol Ther 2020 48(2)237-41


Verification of the effects of capsules containing Allium victorialis subsp. platyphyllum extract on the body temperature of healthy Japanese adults
– A randomized,double-blind,placebo-controlled clinical trial –

T. Kanai, et al.

Jpn Pharmacol Ther 2020 48(2)243-57


Results of stratified analysis limited to healthy subjects on evaluation of cholesterol regulating effect by intake of concentrated red yeast rice capsule
– Randomized double-blind placebo-controlled parallel group comparison –

M. Kageyama, et al.

Jpn Pharmacol Ther 2020 48(2)259-65


Effect of long-term intake on abdominal body fat reduction by Lactobacillus plantarum PIC-NBN22 and fructo‐oligosaccharides in an investigation of a clinical trial
– A randomized, double-blind, placebo-controlled, parallel group study –

N. Nakanishi, et al.

Jpn Pharmacol Ther 2020 48(2)267-81


Effect of Lactobacillus plantarum PIC-NBN22 and fructo – oligosaccharides on bowel movement and on intestinal flora in normal healthy adults with a tendency toward constipation
– A randomized, double-blind, placebo-controlled, cross-over trial –

F. Yajima, et al.

Jpn Pharmacol Ther 2020 48(2)283-90


Effect of ingestion of α-linolenic acid in subjects with high-normal blood pressure
– A double blind, parallel, placebo-controlled study –

N. Nosaka, et al.

Jpn Pharmacol Ther 2020 48(2)291-304


Regular intake of Japanese traditional rice fermented beverage, Koji amazake for 4 weeks decreases systolic blood pressure
– A randomized, double-blind, placebo-controlled, parallel-group comparative study –

K. Kikushima, et al.

Jpn Pharmacol Ther 2020 48(2)305-12


The effects of food containing a labdane type diterpenoid (Labdane) on knee joint problems of healthy adults

A. Yamasaki, et al.

Jpn Pharmacol Ther 2020 48(2)313-7