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Vol. 37　No. 8　2009

Using and validating surrogate endpoints toward accelerated approvals

H. Origasa, et al.

Jpn Pharmacol Ther 2009　37(8) 633-9

Effects of opioid analgesics on the sleep-wake rhythm in rats

T. Ishida, et al.

Jpn Pharmacol Ther 2009　37(8) 643-7

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Effect of an H₁-receptor antagonist, fexofenadine hydrochloride, on substance P secretion from sensory neurons in vitro

A. Furuya, et al.

Jpn Pharmacol Ther 2009　37(8) 649-56

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Effects of Shakuyaku-kanzo-toh long term administration on body weight, blood pressure and electrolytes（Na^＋, K^＋, Cl^－）in rats

T. Shiboi, et al.

Jpn Pharmacol Ther 2009　37(8) 657-61

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Pharmacological effects of combination treatment of salmeterol and fluticasone propionate on physiological changes（increase of airway resistance and inflammatory cell infiltration into bronchi and alveoli）induced by exposure to tobacco smoke in mice and guinea pigs

H. Yoshizaki, et al.

Jpn Pharmacol Ther 2009　37(8) 665-75

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Safety studies of extract from the leaf and stem of yacon

T. Narita, et al.

Jpn Pharmacol Ther 2009　37(8) 677-90

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Comparative pharmacokinetic study of intravenous（IV）or subcutaneous（SC）administration of KRN5702（Epoetin alfa） produced by bovine serum or serum-free culture

T. Yamamoto, et al.

Jpn Pharmacol Ther 2009　37(8) 691-8

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