Objectives　We examined the suppressive effect of the tablet containing Salacia chinensis extract（SCE）on postprandial blood glucose.
Methods　We performed a randomized double-blind and crossover trial in 32 human volunteers with fasting blood glucose levels between 100 and 125 mg/dL. The volunteers were orally administered the tablet containing SCE or placebo followed by a meal. The blood glucose and insulin levels were measured after meal with time.
Results　Intake of SCE significantly suppressed the increase of postprandial blood glucose level at 30 minutes after meal compared with placebo. The AUC of the blood glucose levels up to 3 hours in SCE treatment group was also significantly lower than placebo group. In addition, the serum insulin levels and AUC in the subjects administered SCE were also significantly lower than that of placebo.
Conclusion　The data indicate that the tablet containing SCE suppressed the increases of postprandial blood glucose and insulin in the subjects with a fasting blood glucose level between 100 and 125 mg/dL. Therefore SCE is considered to be helpful and useful for the prevention of diabetes for the people with higher blood glucose.