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Japanese Pharmacology & Therapeutics(JPT)

Vol. 50 No. 5 2022

■ ORIGINAL ARTICLES

Characterization of the relationship between the pharmacokinetics of tolvaptan and the pharmacodynamic effects on urine volume after single and multiple doses of intravenous OPC—61815 and oral tolvaptan
– A population pharmacokinetic/pharmacodynamic model –

M. Masuda, et al.

Jpn Pharmacol Ther 2022 50(5)765-79


Antiviral effect of functional food nattokinase(NK)
– Degradation of novel coronavirus spike protein and influenza virus hemagglutinin(HA)protein –

M. Ohta, et al.

Jpn Pharmacol Ther 2022 50(5)781-7


Food containing rice bran fermented product improve glucose metabolism
– A randomized, double‒blind, placebo‒controlled study –

S. Yoshino, et al.

Jpn Pharmacol Ther 2022 50(5)791-9


Effects of consuming food containing matured red ginseng extract on sleep quality among healthy Japanese adults
– A randomized, placebo‒controlled, double‒blind, parallel‒group comparison study –

K. Mihara, et al.

Jpn Pharmacol Ther 2022 50(5)801-15


Effects of a soy isoflavone and lactobionic acid on skin viscoelasticity and stratum corneum hydration in healthy adult women who are aware of dryness
– A randomized, double‒blind, placebo‒controlled, parallel‒group study –

R. Akagi, et al.

Jpn Pharmacol Ther 2022 50(5)817-33


Effects of mature okra seeds extract on skin elasticity in healthy subjects
– A randomized, placebo controlled, double‒blind, paralleled study –

T. Nakano, et al.

Jpn Pharmacol Ther 2022 50(5)835-41


Efficacy and safety of intake of food containing Lactiplantibacillus plantarum subsp. plantarum strain N793 on thinning hair

A. Mori-Ichioka, et al.

Jpn Pharmacol Ther 2022 50(5)843-54


Improvement of iron profile by long‒term intake of banana in obese Japanese
– Randomized parallel‒group comparison study –

M. Itoh, et al.

Jpn Pharmacol Ther 2022 50(5)855-63


Safety evaluation of overintake of egg white hydrolysate

M. Oe, et al.

Jpn Pharmacol Ther 2022 50(5)865-9


Randomized controlled trial of the effects of Tongkat Ali intake on stress markers and sleep quality in healthy Japanese adults

H. Toyama, et al.

Jpn Pharmacol Ther 2022 50(5)871-6


Effect of Greek yogurt on body weight, body composition, muscle strength, physical function, and subjective evaluation parameters

A. Ogawa, et al.

Jpn Pharmacol Ther 2022 50(5)877-86


The effect of a tamarind and turmeric mixture on knee and/or back discomfort in Japanese adults

T. Kanai, et al.

Jpn Pharmacol Ther 2022 50(5)887-900


Dietary glucosylceramide extracted from potato improves skin conditions
– Randomized, double‒blind, placebo‒controlled, parallel‒group study –

M. Suto, et al.

Jpn Pharmacol Ther 2022 50(5)901-14


Effects of intake of foods containing Bifidobacterium breve N106 on muscles
– Open‒label, single‒arm study –

A. Igi, et al.

Jpn Pharmacol Ther 2022 50(5)915-25


Improvement effect of intestinal environment, defecation symptoms and skin quality by inulin‒containing supplements

M. Takahashi, et al.

Jpn Pharmacol Ther 2022 50(5)927-35


Effects of ursolic acid in seaberry extract on the frequency of daily urination in healthy Japanese subjects

T. Takara, et al.

Jpn Pharmacol Ther 2022 50(5)937-41