Objectives　The objective of this study was to investigate the effect of continuous consumption of the beverage containing quercetin glucosides（enzymatically modified isoquercitrin）on body fat accumulation in obese subjects.
Methods　A randomized, placebo-controlled, double blind intervention trial was conducted on 120 subjects with 25≦body mass index＜30 kg/m². They were divided into two groups and ingested either active beverage containing 110 mg quercetin glucosides or placebo beverage for 24 weeks.
Results　Abdominal total fat area, visceral fat area, and subcutaneous fat area by computed tomography reduced significantly in active beverage group compared to placebo beverage group. No adverse events related to test beverages were observed.
Conclusions　These results suggest that continuous consumption of the beverage containing quercetin glucosides reduced body fat safely, and might be useful for prevention and improvement of obesity and metabolic syndrome.